Prof. Xuefei Huang
Professor in Chemistry at Michigan State University
425A Chemistry building
East Lansing MI, 48824
Office: 517-355-9715 x 329
Email: xuefei@chemistry.msu.edu
Biography
I. Education History
B.S. 1994 (Chemistry) University of Science and Technology of China (USTC)
M.A. 1996, M. Phil. 1998 Columbia University in the City of New York
Ph.D. 1999 (Chemistry) Columbia University in the City of New York
II. Professional Experience
1994 - 1999 Graduate Research Assistant, ColumbiaUniversity
1999 - 2001 Postdoctoral Fellow, The Scripps Research Institute
2001 - 2002 Postdoctoral Fellow, Department of Chemistry, ColumbiaUniversity
2002 – 2006 Assistant Professor, Department of Chemistry, University of Toledo
2006 – 2008 Associate Professor, Department of Chemistry, University of Toledo
2008 – 2012 Associate Professor, Department of Chemistry, Michigan State University
2012 –present Professor, Department of Chemistry, Michigan State University
III. Honors Received
1990-1991 People’s Fellowship, USTC
1992 Zhang Zhongzhi Award for Outstanding Undergraduates, USTC
1993 Yi Lida Award for Outstanding Laboratory Works, USTC
1994 – 1999 Faculty Fellowship, Columbia University
1999 Pegram Award for Excellent Graduate Studies, Columbia University
2006 – 2011 NSF CAREER award
2007 Dion D. Raftopoulos Outstanding Research Award, Sigma Xi, Univ. of Toledo
2008 Distinguished Faculty Award, Chinese-American Chemistry Prof. Association
2009 New Investigator Award, American Chemical Society Carbohydrate Division
2011 Horace S. Isbell Award, American Chemical Society Carbohydrate Division
IV. Professional Affiliations
American Chemical Society
American Chinese Chemistry Professor Association
V. Courses Taught
General Chemistry Laboratory
Organic Chemistry I & II
Advanced Organic Chemistry
Spectroscopic Methods & Analysis
Organic Synthesis
Physical Organic Chemistry
VI.Fundings
CURRENT SUPPORT
National Cancer Institute, NIH
Title: “Virus-Like Particle Based Antigen Display as Multi-component Anticancer Vaccines”
PI: Xuefei Huang, co-PIs: M.G. Finn (The Scripps Research Institute), Lbachir BenMohammad (UC Irvine) 1/15/2011 – 12/31/2015. Award amount: $2,530,050 (1R01CA149451-01A1) Award amount to PI: ~ $1,200,000
National Institute of General Medical Sciences, NIH
Title: “Chemoenzymatic Synthesis of Heparin and Heparan Sulfate Oligosaccharides”
PI: Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill) 6/1/2010 – 5/31/2014. Award amount: $1,150,000 (R01 GM72667) Award amount to PI: ~ $800,000
National Science Foundation
Title:" Synthesis of Homogeneous Heparan Sulfate Proteoglycans"
PI: Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill) 8/15/2011 – 7/31/2014. Award amount: $390,000 (CHE 1111550). Award amount to PI: ~ $270,000
COMPLETED SUPPORT
National Science Foundation
Title:"CAREER Syntheses of Hyaluronan Oligosaccharides as Biological Probes"
PI: Xuefei Huang, 6/1/2006 – 5/31/2011. Award amount: $525,000 (CHE 0547504).
American Chemical Society Local section Innovative Project Grant
Title: "Science Café"
PI: Xuefei Huang, 6/1/2011 – 5/31/2012. Award amount: $1,600.
American Heart Association, doctoral Fellowship
Title: "Magnetic nanoparticles: Applications in atherosclerotic plaque imaging and targeted drug delivery"
PI: Medha Kamat; Advisor: Xuefei Huang, 7/2009 – 10/2011 Award Amount: $95,224
National Institute of General Medical Sciences, NIH
Title: “Development of New Carbohydrate Synthesis Methodologies”
PI: Xuefei Huang, 3/1/2005 – 5/31/2010. Award amount: $1,194,834 (R01 GM72667)
American Heart Association, Ohio Valley Affiliates Pre-doctoral Fellowship
Title: “Design, Synthesis and Biological Evaluation of Hyaluronic Oligosaccharides as Potent Inhibitors of CD44”
PI: Kheireddine El-boubbou; Advisor: Xuefei Huang, 7/2007 – 6/2009. Award Amount: $42,000
National Science Foundation
Title: “Ohio Consortium for Undergraduate Research: Research Experiences to Enhance Learning (REEL)”
PI: Prabir Dutta (Ohio State University), UT PI: Xuefei Huang, 9/1/2005 – 8/31/2008. Award amount: $1,337,196 (CHE 0532250).
National Science Foundation
Title: “A Novel Approach to Antibiotic and Anti-biofouling Activities of Natural Phenols"
PI: Dong-Shik Kim, co-PI: Xuefei Huang, 9/1/2006 – 8/31/2009. Award amount: $185,471
DARPA, DOD
Title: “Novel Sensors for Chemical and Bio-Defense”
PI: Jon Kirchhoff, one of several co-PIs: Xuefei Huang. 12/2006 – 1/2008
Award Amount: $1,000,000
University of Toledo, Interdisciplinary Research Award
Title: “Development Towards Carbohydrate-Based Cancer Vaccines”
PI: Steven Sucheck, one of four co-PIs: Xuefei Huang. 5/2007 – 8/2008
Award Amount: $50,000
University of Toledo, Program for Academic Excellence
Title: “Saturday Morning Science: A Community Outreach Program”
PI: Xuefei Huang, co-PI: R. Alejandra Lukaszew. 9/2006 – 8/2008
Award Amount: $4,500
National Institute of General Medical Sciences, NIH
Title: “Development of New Carbohydrate Synthesis Methodologies – Minority Supplement”
PI: Xuefei Huang, 1/1/2006 – 12/31/2007. Award amount: $86,983 (R01 GM72667-S1)
Pardee Foundation
Title: “Syntheses of Tumor Associated Carbohydrate Antigens Using the Iterative One-pot Strategy”
PI: Xuefei Huang, 12/9/2004 – 3/31/2006. Award Amount: $60,000
University of Toledo, Interdisciplinary Research Award
Title: “Design of Novel Nano- to Microscale Sensors for Biochemical Applications”
PI: Jon Kirchhoff, one of four co-PIs: Xuefei Huang. 6/2005 – 5/2006.
Award Amount: $30,000
deArceMemorial Endowment Fund
Title: “A Novel Synthesis of an Anticancer Glycolipid by Chemical Glycosylation in water with Colloidal Dispersions”
PI: Xuefei Huang, 5/2003 – 4/2004. Award Amount: $12,650
VII. Service
A) Activities at the University of Toledo
Graduate recruiting committee, member 2002 - 2008
Colloquium committee, chair 2003 - 2004
Faculty search committee for chemistry department 2002 – 2005
Faculty search committee for medicinal chemistry dept. 2006
Departmental library liaison 2004 – 2008
Chair advisory committee 2004 – 2005, 2006 - 2008
Departmental personnel committee 2007 - 2008
Departmental merit committee 2007 - 2008
College of Arts & Sciences council, member 2004 – 2007
B) Activities at Michigan State University
Chair advisory committee 2008 – 2010
Graduate student examination committee 2008 – present
Awards committee 2009 – 2011
Departmental colloquium committee chair 2011
Graduate admission committee 2010 – present
Departmental colloquium committee chair 2012- present
C) Other Professional Activities
Oct. 2007 Ad hoc member, NIH study sections HT
June 2008 Ad hoc member, NIH study section SBCA
Oct. 2008 NSF CAREER proposal review panelist
June 2009 Member, NIH study section ZRG1 BCMB-B
July 2009 Member, NIH study section ZRG1 BCMB-A
July 2009 Member, NIH study section “Expanding the Chemical Space for Carbohydrates"
Oct. 2009 Member, NIH study section ZRG1 BCMB
March. 2010 Member, NIH study section ZRG1 BCMB-B
May 2010 Member, NIH study section ZRG1 CB-B
Oct. 2011 Member, Mail Reviewer, NIH K99 review panel
Mar. 2012 Member, Mail Reviewer, NIH special emphasis panel ZCA1 SRLB-9
Feb 2013 Member, Member, NIH study section MSFE
Review proposals for:
National Science Foundation, National Institutes of Health, Petroleum Research Foundation of the American Chemical Society, Bicentennial Program in Science and Technology of Chile, Natural Sciences and Engineering Research Council of Canada (NSERC), Chilean National Commission for Science and Technology Research, North Carolina Biotechnology Center, Ohio Cancer Associate, Central Michigan University, Austrian Programme for Advanced Research and Technology, Danish Council for Independent Research, Israel Science Foundation
2005
Organizer of the 1st Annual Midwest Carbohydrate and Glycobiology Symposium, Toledo, OH
2006
Section chair, 2nd Annual Midwest Carbohydrate and Glycobiology Symposium, Detroit, MI
2007
Discussion leader, Gordon Research Conference on Carbohydrates
2007
Section chair, 3rd Annual Midwest Carbohydrate and Glycobiology Symposium, Columbus, OH
2008 – present
Board member of the Chinese-American Chemistry Professor Association
2009
Section chair, 5th Annual Midwest Carbohydrate and Glycobiology Symposium, Cincinnati, OH
2010 - 2011
Secretary of the American Chemical Society Carbohydrate Division
2010
Organizer and Chair of "Petite and Sweet: Glyco-nanotechnology as a Bridge to New Medicines" symposium, ACS 240th National Meeting, Boston, MA
2010
Chair-elect, American Chemical Society MSU local section
2010
Section chair, 6th Annual Midwest Carbohydrate and Glycobiology Symposium, Toledo, OH
2011
Chair, American Chemical Society MSU local section
2011
Organizer of the 7st Annual Midwest Carbohydrate and Glycobiology Symposium, East Lansing, MI
2011
One of the two editors for ACS Symposium book, "Glyco-nanotechnology as a Bridge to New Medicines" (Dr. Joseph Barchi from NCI is the other editor)
2011 - present
Member, Editorial Advisory Board, Carbohydrate Research
2012 - 2013
Program Chair of the American Chemical Society Carbohydrate Division
2012 - present
Associate Editor, Journal of Carbohydrate Chemistry
Review manuscripts for:J. Am. Chem. Soc., J. Org. Chem., Chem. Commun., Org. Lett., Angew. Chemie., Tetrahedron, Tetrahedron Lett., Eur. J. Org. Chem., Synthesis, Adv. Synth. Catal., Cancer Immun. Immunother., Carbohydr. Res., Chirality, Bioorg. Med. Chem., Lett. Org. Chem., Curr. Med. Chem., J. Carbohydr. Chem., Org. Biomol. Chem., Biochemistry, Mol. Biosys., Med. Chem. Rev., J. Med. Chem., Molecular Diversity, Science China Chemistry, Anal. Chem., Analyst, Glycobiology, Proc. Nat. Acad. Sci. USA, Nanoscale, Appl. Microbiol. Biotech., Adv. Func. Mater., Int. J. Mol. Sci.
Review various faculties for tenure and/or promotion
D) Service to the Community
Give chemistry demos during National Chemistry Day 2007 - 2008
Judge, Northwest District Science Day 2005
Speaker and organizer, Saturday Morning Sciences, a community outreach seminar program 2005 - 2008
Frontiers in Science program for secondary science teachers 2011
VIII. Publications
Please click here for the complete list of journal articles, patents and presentations at scholarly meetings
IX. Invited seminars
2004
Department of Medicinal and Biological Chemistry, The University of Toledo
Department of Chemistry, KenyonCollege
Department of Chemistry, WrightStateUniversity
2005
Department of Chemistry, YoungstownStateUniversity
Department of Chemical and Environmental Engineering, The University of Toledo
Department of Chemistry, University of Georgia
Department of Chemistry, Georgia State University
Department of Chemistry, Wayne State University
Department of Chemistry, University of Guelph
2006
Department of Chemistry, University of Akron
Department of Chemistry, University of California, Davis
Department of Chemistry, Cleveland State University
Department of Chemistry, Duke University
Department of Chemistry, University of South Carolina
Department of Chemistry, North Carolina State University
Department of Chemistry, West Virginia University
Department of Chemistry, Pennsylvania State University
Department of Chemistry, Michigan State University
Department of Chemistry, Columbia University
Department of Chemistry, Hunter College, City University of New York
2007
Department of Bioengineering, University of Toledo
Department of Chemistry, John Carroll University
Department of Medicinal and Biological Chemistry, University of Toledo
Department of Chemistry, Tulane University
National Institutes of Health, NIH Workshop on Carbohydrates
Faculty of Agriculture and Life Science, Hirosaki University, Japan
National Research Laboratory of Natural and Biomimetic Drug, Peking University, China
2008
Department of Chemistry, Oakland University
National Institutes of Health, NIH Glycoscience day
School of Chemistry and Materials Science, USTC, Hefei, China
Department of Chemistry, University of New Mexico
Department of Chemistry, University of Missouri, St. Louis
2009
Department of Chemistry and Chemical Biology, Cornell University
Department of Chemistry, Binghamton University
Laboratory of Medicinal Chemistry, National Cancer Institute
National Institutes of Health, NIH Workshop on Carbohydrate Microarray Development
2010
Department of Chemistry, University of New Orleans
Department of Chemistry, Osaka University, Japan
Department of Biomedical Engineering, University of Michigan
Department of Medicinal Chemistry, University of North Carolina, Chapel Hill
2011
Department of Chemistry, Purdue University
Shanghai Institute of Organic Chemistry, China
Department of Chemistry, Shandong University, China
Department of Chemical Biology, Xiamen University, China
Department of Chemistry, Shanghai Jiaotong University, China
2012
Department of Chemistry, Central Michigan University
Department of Melanoma Medical Oncology Research, M. D. Anderson Cancer Center
Department of Chemistry, Brown University
2013
Department of Chemistry, University of Pittsburgh