COMPLETED SUPPORT

National Institute of General Medical Sciences, NIH

Title: “Homogeneous Heparan Sulfate Glycopeptides: Synthetic and Functional Studies”

PI: Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill)6/1/2015 – 12/31/2020. Award amount: $1,157,264 (R01 GM72667)

National Institute of General Medical Sciences, NIH

Title: “Stereoselective Assembly of Challenging Glycosidic Linkages with Earth-Abundant Metal Catalysts”

PI: Hao Xu (Georgia State Univ.); co-PI: Xuefei Huang 5/1/2018 – 4/30/2020. Award amount: ~ $432,650 (1R21GM128442-01)

Michigan Economic Development Corp

Title: “A Novel Vaccine Strategy to Target Breast Cancer Based on Proprietary Mutant Bacteriophage Qβ-MUC1 Conjugate Designed to Maximize Immunogenicity while Minimizing Side Effects”

PI: Xuefei Huang; 2/1/2019 – 8/31/2020. Award amount: $195,689

National Institute of General Medical Sciences, NIH

Title: “Expedited Synthesis of Glycosaminoglycans Containing Defined Sulfation Domains”

PI: Linda Hsieh-Wilson (California Institute of Technology, Contact PI) and Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill) 7/1/2015 – 5/31/2019. Award amount: $2,481,666 (U01 GM116262)

National Science Foundation

Title: “Synthetic and Biological Studies of Chondroitin Sulfate Oligosaccharides and Glycopeptides”

PI: Xuefei Huang 8/1/2015 – 7/31/2018. Award amount: $540,000 (CHE 1507226).

National Science Foundation

Title: “Development of Functionalized Membranes to Enhance Antibody Sequencing and Screening”

PI: Merlin Bruening (MSU), co-PI: Xuefei Huang, 9/1/2015 – 8/31/2018. (CHE 1506315).

National Institute of Biomedical Imaging and Bioengineering, NIH

Title: “MRI Contrast Agents for in vivo Monitoring of Stem Cell Differentiation”

PI: Erik Shapiro (MSU); one of the two co-PIs: Xuefei Huang 7/1/2014 – 6/30/2016. (R21 EB017881)

National Cancer Institute, NIH

Title: “Virus-Like Particle Based Antigen Display as Multi-component Anticancer Vaccines”

PI: Xuefei Huang, co-PIs: M.G. Finn (Georgia Institute of Technology), Lbachir BenMohammad (UC Irvine) 1/15/2011 – 12/31/2015. (R01 CA149451)

National Institute of General Medical Sciences, NIH

Title: “Uncovering the Controlling Mechanisms in Heparan Sulfate Biosynthesis”

PI: Jian Liu (UNC Chapel Hill); co-PIs: Robert J. Linhardt (Rensselaer Institute of Technology), Xuefei Huang 9/1/2013 – 5/31/2017. (U01 GM102137)

National Institute of General Medical Sciences, NIH

Title: “Homogeneous Heparan Sulfate Glycopeptides: Synthetic and Functional Studies”

PI: Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill) 6/1/2015 – 2/28/2019. (R01 GM72667)

National Institute of General Medical Sciences, NIH

Title: “Expedited Synthesis of Glycosaminoglycans Containing Defined Sulfation Domains”

PI: Linda Hsieh-Wilson (California Institute of Technology, Contact PI) and Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill) 7/1/2015 – 5/31/2019. (U01 GM116262)

National Institute of Allergy and Infectious Diseases, NIH

Title: “Virus Like Particles as Carriers for Carbohydrate Based Anti-Salmonella Vaccines”

PI: Xuefei Huang 8/1/2015 – 7/31/2017. (R03 AI111054)

National Science Foundation

Title: “Synthetic and Biological Studies of Chondroitin Sulfate Oligosaccharides and Glycopeptides”

PI: Xuefei Huang 8/1/2015 – 7/31/2018. (CHE 1507226).

National Institute of General Medical Sciences, NIH

Title: “Chemoenzymatic Synthesis of Heparin and Heparan Sulfate Oligosaccharides”

PI: Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill) 6/1/2010 – 5/31/2014. Award amount: $1,150,000 (R01 GM72667) Award amount to PI: ~ $800,000

National Science Foundation

Title:" Synthesis of Homogeneous Heparan Sulfate Proteoglycans"

PI: Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill) 8/15/2011 – 7/31/2014. Award amount: $390,000 (CHE 1111550). Award amount to PI: ~ $270,000

National Science Foundation

Title:"CAREER Syntheses of Hyaluronan Oligosaccharides as Biological Probes"

PI: Xuefei Huang, 6/1/2006 – 5/31/2011. Award amount: $525,000 (CHE 0547504).

American Chemical Society Local section Innovative Project Grant

Title: "Science Café"

PI: Xuefei Huang, 6/1/2011 – 5/31/2012. Award amount: $1,600.

American Heart Association, doctoral Fellowship

Title: "Magnetic nanoparticles: Applications in atherosclerotic plaque imaging and targeted drug delivery"

PI: Medha Kamat; Advisor: Xuefei Huang, 7/2009 – 10/2011 Award Amount: $95,224

National Institute of General Medical Sciences, NIH

Title: “Development of New Carbohydrate Synthesis Methodologies”

PI: Xuefei Huang, 3/1/2005 – 5/31/2010. Award amount: $1,194,834 (R01 GM72667)

American Heart Association, Ohio Valley Affiliates Pre-doctoral Fellowship

Title: “Design, Synthesis and Biological Evaluation of Hyaluronic Oligosaccharides as Potent Inhibitors of CD44”

PI: Kheireddine El-boubbou; Advisor: Xuefei Huang, 7/2007 – 6/2009. Award Amount: $42,000

National Science Foundation

Title: “Ohio Consortium for Undergraduate Research: Research Experiences to Enhance Learning (REEL)”

PI: Prabir Dutta (Ohio State University), UT PI: Xuefei Huang, 9/1/2005 – 8/31/2008. Award amount: $1,337,196 (CHE 0532250).

National Science Foundation

Title: “A Novel Approach to Antibiotic and Anti-biofouling Activities of Natural Phenols"

PI: Dong-Shik Kim, co-PI: Xuefei Huang, 9/1/2006 – 8/31/2009. Award amount: $185,471

DARPA, DOD

Title: “Novel Sensors for Chemical and Bio-Defense”

PI: Jon Kirchhoff, one of several co-PIs: Xuefei Huang. 12/2006 – 1/2008

Award Amount: $1,000,000

University of Toledo, Interdisciplinary Research Award

Title: “Development Towards Carbohydrate-Based Cancer Vaccines”

PI: Steven Sucheck, one of four co-PIs: Xuefei Huang. 5/2007 – 8/2008

Award Amount: $50,000

University of Toledo, Program for Academic Excellence

Title: “Saturday Morning Science: A Community Outreach Program”

PI: Xuefei Huang, co-PI: R. Alejandra Lukaszew. 9/2006 – 8/2008

Award Amount: $4,500

National Institute of General Medical Sciences, NIH

Title: “Development of New Carbohydrate Synthesis Methodologies – Minority Supplement”

PI: Xuefei Huang, 1/1/2006 – 12/31/2007. Award amount: $86,983 (R01 GM72667-S1)

Pardee Foundation

Title: “Syntheses of Tumor Associated Carbohydrate Antigens Using the Iterative One-pot Strategy”

PI: Xuefei Huang, 12/9/2004 – 3/31/2006. Award Amount: $60,000

University of Toledo, Interdisciplinary Research Award

Title: “Design of Novel Nano- to Microscale Sensors for Biochemical Applications”

PI: Jon Kirchhoff, one of four co-PIs: Xuefei Huang. 6/2005 – 5/2006.

Award Amount: $30,000

deArceMemorial Endowment Fund

Title: “A Novel Synthesis of an Anticancer Glycolipid by Chemical Glycosylation in water with Colloidal Dispersions”

PI: Xuefei Huang, 5/2003 – 4/2004. Award Amount: $12,650