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Papers
Cox, M. C.; Barnham, K. J.; Frenkiel, T. A.; Hoeschele, J. D.; Mason, A. B.;
He, Q-Y; Woodworth, R. C.; Sadler, P. J.
"Identification of Platination Sites on Human Serum Transferrin Using
13C and 15N NMR Spectroscopy"
J. Biol. Inorg. Chem. 1999, 4, 621-631.
Hoeschele, J. D.; Showalter, H. D. H.; Kraker, A. J.; Elliott, W. L.;
Roberts, B. J.; Kampf, J. W.
"Synthesis, Structural Characterization, and Antitumor Properties of a Novel Class
of Large-Ring Platinum(II) Chelate Complexes Incorporating the
cis-1,4-Diaminocyclohexane Ligand in a Unique Locked Boat Conformation"
J. Med. Chem. 1994, 37, 2630-2636.
Ekhato, I. V.; Hoeschele, J. D.; Huang, C. C.; Nanavaty, B.; and Lee, H. T.
"Synthesis of the Antitumor Agent (CI-973) {[SP-4-3-(R)]-[Cyclobutane-
dicarboxylato(2)](2-methyl-1,4-[4-14C]butanediamine-N,N')platinum}"
J. Labelled Compounds and Radiopharmaceuticals 1993 33, 1083-1089.
Hoeschele, J. D.; Roy, A. K.; Pecoraro, V. L.; Carver, P. L.
"In Vitro Analysis of the Interaction Between Sucralfate and Ketoconazole"
Antimicrob. Agents Chemother. 1994, 38, 319-325.
Shaw III, C. F.; Isab, A. A.; Hoeschele, J. D.; Starich, M.; Locke, J.; Schulteis, P.;
Xiao, J.
"Oxidation of the Phosphine from the Auranofin Analog,
Triisopropylphosphine(2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranosato-S)gold(I),
via a Protein-bound Phosphonium Intermediate"
J. Amer. Chem. Soc. 1994, 116, 2254-2260.
Wolfgang, G. H. I.; Dominick, M. A.; Walsh, K. M.; Hoeschele, J. D.; Pegg, D. G.
"Comparative Nephrotoxicity of a Novel Platinum Compound, Cisplatin, and
Carboplatin in Male Wistar Rats"
Fundamental and Applied Toxicology 1994, 22, 73-79.
Qu, Y.; Appleton, T. G.; Hoeschele, J. D.; Farrell, N.
"Cisplatin as Synthon. Synthesis and Characterization of Triplatinum Complexes
Containing Three cis-Pt(amine)2 Units Linked in a Linear Fashion"
Inorg. Chem. 1993, 32, 2591-2593.
Root, C.; Hoeschele, J. D.; Cornman, C. R.; Kampf, J. W.; Pecoraro, V. L.
"Structural and Spectroscopic Characterization of Dioxovanadium(V) Complexes With
Asymmetric Schiff Base Ligands"
Inorg. Chem. 1993, 32, 3855-3861.
Cornman, C. R.; Colpas, G. J.; Hoeschele, J. D.; Kampf, J. W.; Pecoraro, V. L.
"Implications for the Spectroscopic Assignment of Vanadium Biomolecules: Structural
and Spectroscopic Characterization of Monooxovanadium(V) Complexes Containing
Catecholate and Hydroximate-Based Non-Innocent Ligands"
J. Am. Chem. Soc. 1992, 114, 9925-9933.
Kraker, A. J.; Hoeschele, J. D.; Elliott, W. L.; Showalter, H. D. H.; Sercel, A. D.;
Farrell, N. P.
"Anticancer Activity in Murine and Human Tumor Cell Lines of Bis(platinum) Complexes
Incorporating Straight-Chain Aliphatic Diamine Linker Groups"
J. Med. Chem. 1992, 35, 4526-4532.
Hoeschele, J. D.; Turner, J. E.; England, M. Wendy
"Inorganic Concepts Relevant to Metal Bonding, Activity, and Toxicity in a
Biological System"
The Science of the Total Environment 1991, 109/110, 477-492.
Hoeschele, J. D.; Kraker, A. J.; Qu, Y.; Van Houten, B.; Farrell, N.
"Bisplatinum Complexes: Chemistry, Antitumor Activity, and DNA Binding"
Twenty-third Jerusalem Symposium on Quantum Chemistry and Biochemistry, Molecular
Basis of Specificity and Nucleic Acid-Drug Interactions, Pullman, B. and Jortner, J.
(eds.), 1990, 301-321, Kluwer Academic Publishers, The Netherlands.
Hoeschele, J. D.; Farrell, N.; Turner, W. R.; Rithner, C.
"Synthesis and Characterization of Diastereomeric
(Substituted-Iminodiacetato)(1,2-diaminocyclohexane)platinum(II) Complexes"
Inorg. Chem. 1988, 27, 4106-4113.
Isab, A. A.; Shaw III, C. F.; Hoeschele, J. D.; Locke, J.
"Reactions of Trimethylphosphine Analogues of Auranofin with Bovine Serum Albumin"
Inorg. Chem. 1988, 27, 3588-3592.
Hoeschele, J. D.
"Structure-Activity Relationships for Diamineplatinum(II) Complexes as Regards
Antitumor Activity and Toxicity"
Proceedings of the Third International Workshop on Quantitative Structure-Activity
Relationships in Environmental Toxicology (QSAR 88). May 1988. N.T.I.S. U.S. Dept.
Commerce, CONF-880520--(DE88013180)
Raudaschl, G.; Lippert, B.; Hoeschele, J. D.; Howard-Lock, H. E.; Lock, C. J. L.;
Pilon, P.
"Adduct Formation of cis-(NH3)2PtX2
(x=Cl-,I-) with Formamides and the Crystal Structures of
cis-(NH3)2PtCl2*(CH3)2NCHO.
Application for the Purification of the Antitumor Agent Cisplatin"
Inorganica Chim. Acta 1985, 106, 141-149.
Zelazowski, A. J.; Garvey, J. S.; Hoeschele, J. D.
"The In Vivo and In Vitro Binding of Platinum to Metallothionein"
Arch. Biochem. Biophys. 1984, 229, 246-252.
Hoeschele, J. D.; Ferren, L. A.; Roberts, J. A.; Whitfield, L. R.
"Biodistribution and Pharmacokinetics of 195mPt-Labeled
cis-Dichloro-trans-Dihydroxo-bis-(isopropylamine)okatubyn(IV), CHIP, in
the Normal Female Fischer 344 Rat"
in Platinum Coordination Complexes in Cancer Chemotherapy, M. P. Hacker, E. B. Douple,
I. H. Krakoff (Eds.), Martinus Nijhoff Publishing, Boston, 1984, 103-113.
Rahn, R. O.; Chang, S. S.; Hoeschele, J. D.
"Adducts Formed Between Deoxyguanosine and cis-Dichlorodiammineplatinum(II):
Separation by Means of Cation-Exchange Chromatography"
J. Inorg. Biochem. 1983, 18, 279-290.
Pretorius, R. G.; Hacker, N. F.; Berek, J. S.; Gotf, L. C.; Hoeschele, J. D.; Butler,
T. A.; Lagasse, L. G.
"Pharmacokinetics of Intra-Peritoneal Cisplatin in Refractory Ovarian Carcinoma"
Cancer Treat. Rep. 1983, 67, 1085-1092.
Hoeschele, J. D.; Ferren, L. A.; Roberts, J. A.
"Synthesis of 195Au-Labeled Structural Analogs of the Antirheumatoid
Agent, Auranofin (AF),
[Triethylphosphinegold(I)(2,3,4,6-Tetra-O-Acetyl-1-Thio-β-D-Glucopyranoside)] and
Preliminary Tissue Distribution Studies of AF in rats"
Proceedings, International Symposium on the Synthesis and Applications of Labeled
Compounds, Elsevier, Amsterdam, Neth., William P. Duncan and Alexander B. Susan (Eds.)
1983, Vol 2, pp 353-354.
Turner, J. E.; Lee, E. H.; Jacobson, K. B.; Christie, N. T.; Williams, M. W.; Hoeschele,
J. D.;
"Investigation of Correlations Between Chemical Parameters of Metal Ions and Acute
Toxicity in Mice and Drosophila"
The Science of the Total Environment 1983, 28, 343-354.
Raudaschl, G.; Lippert, B.; Hoeschele, J. D.
"A Simple Procedure for Purifying the Antitumor Agent
cis-Pt(NH3)2Cl2 (Cisplatin)"
Inorganic Chim. Acta 1983, 78, L43-L44.
Hoeschele, J. D.; Butler, T. A.; Roberts, J. A.; Guyer, C. E.
"Analysis and Refinement of the Microscale Synthesis of the
195mPt-Labeled Antitumor Drug,
cis-Dichlorodiammineplatinum(II), cis-DDP"
Radiochimica Acta 1982, 31, 27-36.
Williams, M. W.; Hoeschele, J. D.; Turner, J. E.; Jacobson, K. B.; Christie, N. T.;
Paton, C. L.; Smith, L. H.; Witschi, H. H. R.; Lee, E. H.
"Chemical Softness and Acute Metal Toxicity in Mice and Drosophila"
Toxicology and Applied Pharmacology 1982, 63, 461-469.
Pretorius, R. G.; Petrilli, E. S.; Kean, C.; Ford, L. C.; Hoeschele, J. D.; Lagasse, L. D.
"A Comparison of the Intravenous and Intraperitoneal Routes of Administration of
cis-platinum in Dogs"
Cancer Treatment Reports 1981, 65, 1055-1062.
Lagasse, L. D.; Pretorius, R. G.; Petrilli, E. S.; Ford, L. C.; Hoeschele, J. D.; Kean, C.
"The Metabolism of cis-Dichlorodiammineplatinum(II): Distribution, Clearance,
Toxicity"
Amer. J. Obstetrics and Gynecology 1981, 139, 791-798.
Alberts, D. S.; Peng, Y-M.; Chen, H-S. G.; Moon, T. E.; Cetas, T. C.; Hoeschele, J. D.
"Therapeutic Synergism of Hyperthermia-cis-Platinum in a Mouse Tumor Model"
J. Nat. Cancer Inst. 1980, 65, 455-461.
Johnson, N. P.; Hoeschele, J. D.; Rahn, R. O.
"Kinetic Analysis of the In Vitro Binding of Radioactive cis- and
trans-Dichlorodiammineplatinum(II) to DNA"
Chem.-Biol. Interactions 1980, 30, 151-169.
Johnson, N. P.; Hoeschele, J. D.; Rahn, R. O.; O'Neill, J. P.; Hsie, A. W.
"Mutagenicity, Cytotoxicity, and DNA Binding of Platinum(II) Chloroamines in Chinese
Hamster Ovary Cells"
Cancer Research 1980, 40, 1463-1468.
Rahn, R. O.; Johnson, N. P.; Hsie, A. W.; Lemontt, J. F.; Masker, W. E.; Regan, J. D.;
Dunn Jr., W. C.; Hoeschele, J. D.; Brown, D. H.
"The Interaction of Platinum Compounds with the Genome: Correlation Between Binding
Data and Biological Endpoint"
Dev. Toxicol. Environ. Sci., Series, 6, "The Scientific Basis of Toxicity Assessment,"
Elsevier/North-Holland Biomedical Press, H. P. Witschi (Ed.), 1980, pp 153-163.
Hoeschele, J. D.; Butler, T. A.; Roberts, J. A.
"Correlations of Physico-Chemical and Biological Properties with In Vivo
Biodistribution Data for 195mPt-Labeled Chloroammine-platinum(II)
Complexes"
in the American Chemical Society Symposium Series, 140, "Inorganic Compounds in Biology
and Medicine,"1980, Chapter 11, pp 181-208.
Hoeschele, J. D.; Butler, T. A.; Roberts, J. A.
"Microscale Synthesis and Biodistribution Studies of 195mPt-Labeled
cis-Dichlorodiammineplatinum(II), (cis-DDP)"
Radiopharmaceuticals II: Proceedings of the Second International Symposium on
Radiopharmaceuticals, Society of Nuclear Medicine, New York, NY, 1979, pp 173-182.
Hsie, A. W.; Johnson, N. P.; Couch, D. B.; San Sebastian, J. R.; O'Neill, J. P.;
Hoeschele, J. D.; Rahn, R. O.; Forbes, N. I.
"Quantitative Mammalian Cell Mutagenesis and a Preliminary Study of the Mutagenic
Potential of Metallic Compounds"
in Trace Elements in Human Health and Disease, Intrascience Research Foundation, Raven
Press, N. Kharash (Ed.), New York, NY, 1979, pp 55-69.
Lippard, S. J.; Hoeschele, J. D.
"Binding of cis- and trans-Dichlorodiammine-platinum(II) to the
Nucleosome Core"
Proc. Nat. Acad. Sci. 1979, 76, 6091-6095.
DeSimone, P. A.; Yancey, R. S.; Coupal, J. J.; Butts, J. D.; Hoeschele, J. D.
"The Effect of a Forced Diuresis on the Distribution and Excretion (Via Urine and
Bile) of Platinum When Given as
195mPt-cis-Dichlorodiammineplatinum(II)"
Cancer Treatment Reports 1979, 63, 951-960.
Bourne, D. W. A.; Triplett, J. W.; Hayden, T. L.;DeSimone, P. A.; Hoeschele, J. D.
"Pharmacokinetics of cis-Dichlorodiammineplatinum(II) in Rats Using an External
Loop-Eigenfunction Expansion Technique"
J. Pharm. Sci. 1979, 68, 1571-1572.
Douple, E. B.; Howden, F. M.; Hoeschele, J. D.
"Distribution of Platinum Chemotherapeutic Complexes in Normal Tissues and Tumors"
International Journal of Radiation Oncology Biology-Physics 1979, 5,
1387-1391.
Johnson, N. P.; Hoeschele, J. D.; Kuemmerle, N. P.; Masker, W. E.; Rahn, R. O.
"Effects of Platinum Antitumor Agents and Pyrimidine Dimers on the In Vitro
Replication of T7 DNA"
Chem.-Biol. Interactions 1978, 23, 267-271.
Hoeschele, J. D.; Johnson, N. P.; Rahn, R. O.; Brown, D. H.
"Comparative Distribution/Binding Studies of 195mPt-labeled
Dichlorodiammineplatinum(II), DDP, in the Rat with Emphasis on the Localization in DNA"
Biochemie 1978, 60, 1054.
Douple, E. B.; Hoeschele, J. D.
"Effects of Radiation and Malonato(-)R,R-1,2-Diaminocyclohexane-platinum(II) on Rat
Brain Cells In Situ and In Culture"
Radiation Research 1978, 74, 517.
Stanko, J. A.; Hollis, L. S.; Schreifels, J. A.; Hoeschele, J. D.
"Hydroxide Bridged Complexes of Platinum. Crystal Structure Infrared and X-ray
Photoelectron Spectra of Di-μ-Hydroxo-bis-(Diammineplatinum(II)) Nitrate"
J. Clinical Hematology and Oncology 1977, 7, 138-168.
Cleare, M. J.; Hoeschele, J. D.; McAuliffe, C. A.
"Studies on the Antitumor Activity of Group VIII Transition Metal Complexes"
Proceedings, 16th Int. Conf. Coord. Chem. 1974, 1.8, 3pp.
Cleare, M. J.; Connors, T. A.; Hoeschele, J. D.; Rosenberg, B.; Van Camp, L.
title???
in Platinum Coordination Complexes in Cancer Chemotherapy, Connors, T. A. and Roberts,
J. J. (Eds), Springer-Verlag, New York, 1974, pp 33-34.
Cleare, M. J.; Hoeschele, J. D.
"Studies on the Antitumor Activity of Group VIII Transition Metal Complexes, Part I.
Platinum(II) Complexes"
Bioinorganic Chemistry 1973, 2, 187-210.
Cleare, M. J.; Hoeschele, J. D.
"Antitumor Platinum Compounds - Relationship Between Structure and Activity"
Platinum Metals Rev. 1973, 17, 2-13.
Hoeschele, J. D.; Van Camp, L.
"Whole-Body Counting and the Distribution of 195mPlatinum-Labeled
cis-Dichlorodiammineplatinum(II) in the Major Organs of Swiss White Mice"
Proc. Int. Congr. Chemother. 7th Advan. Antimicrob. Antineoplastic Chemother.,
University Park Press, Baltimore, MD, H. Miroslav (Ed), 1972, Vol 2, 241-242.
Cleare, M. J.; Hoeschele, J. D.
"Studies on Analogs of Antitumor-Active Platinum Complexes"
Proc. Int. Congr. Chemother., 7th Advan. Antimicrob. Antineoplastic Chemother.,
University Park Press, Baltimore, MD, H. Miroslav (Ed), 1972. Vol 2, 193-195.
Hoeschele, J. D.
"The Photochemical Acceleration of the Uranium(IV)-Uranium(VI) Electron Exchange
Reaction"
Ph.D. Thesis, 1970, Diss. Abs. 30, 49588.
Vaughen, V. C. A.; Hoeschele, J. D.
title???
Trans. Am. Nuclear Soc. 1969, 12, 55-56.
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