Repurposing
Enzymes to Construct Biosynthetic Pathways toward Non-natural Bioactive Compounds
The Walker laboratory uses interdisciplinary methods to evaluate the application of enzyme catalysts (acquired from various sources: bacteria, plants, yeast, etc.) with non-native substrates to transform natural compounds or synthetically-derived chemicals to novel products. The genes encoding these enzymes can be transferred to a suitable chassis organism to potentially produce
in vivo an assortment of bioactive molecules. (
Intellectual Property/Technology)
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