Sequential Condensation Reactions

Part 1
Many useful synthetic procedures involve sequences of aldol, Claisen, Michael and Mannich reactions. The following equations describe a few examples. Consider each reaction in turn and try to write a mechanism for the transformation.
By clicking on an equation a plausible mechanism for it will be drawn in the space on the right. Electron pair shifts are designated by magenta arrows.

 

This script written by William Reusch, Dept. of Chemistry, Michigan State University. Please send comments and corrections to whreusch@pilot.msu.edu.

Sequential Condensation Reactions

Part 2
Many useful synthetic procedures involve sequences of aldol, Claisen, Michael and Mannich reactions. The following equations describe a few examples. Consider each reaction in turn and try to write a mechanism for the transformation.
By clicking on an equation a plausible mechanism for it will be drawn in the space on the right. Electron pair shifts are designated by magenta arrows.

 

This script written by William Reusch, Dept. of Chemistry, Michigan State University. Please send comments and corrections to whreusch@pilot.msu.edu.