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Lecture Notes CEM351 FS 2025

(General Chemistry Review: View these YouTube Videos)

NOTE: None of these videos features Prof. Kevin Walker or MSU Chemistry T.A.s. These are select videos from YouTubers that provide a great review of what was learned in General Chemistry, or the videos are instructional. However, for CEM 351, it is assume that you have have taken General Chemistry. These video packs provide different viewpoints and styles of delivery of overlapping material.

Video Pack 1 (3 Parts)

1) General Chemistry Review for Organic Chemistry Part 1 - YouTube

2) General Chemistry Review for Organic Chemistry Part 2 - YouTube

3) General Chemistry Review for Organic Chemistry Part 3 - YouTube

Video Pack 2 (1 Part: recommended to watch in 20 min segments, so the over 1 hr of material is not overwhelming)

1) General Chemistry Review for Organic Chemistry - YouTube

Video Pack 3

1) Functional Groups (Identifying them)

PowerPoint Slides

Chapter 1

Monday, August 25

(slide pack 1 of 4)

Wednesday, August 27

Why “know” the periodic table?

(slide pack 2 of 4)

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Friday, August 29, 2025

(slide pack 3 of 4)

Notes: Friday (August 29, 2025)

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Wednesday, September 03 and Friday, September 05

(slide pack 4 of 4)

Notes: Wednesday (September 03, 2025)

Notes: Friday (September 05, 2025)

Notes: Friday (September 01, 2023)

Video: (September 01, 2023)

Chapter 2 (slide pack)

Notes: Monday (September 08, 2025)

Partial worksheet from Class (Explanation)

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Notes: Wednesday (September 10, 2025)

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Notes: Friday (September 12, 2025)

Common name substituent (mnemonics)

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Chapter 2 (end) and Chapter 3 (slide pack):

Newman Projections and Monohalogenation Reactions (Radical Chemistry)

Notes: Monday (September 15, 2025)

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Notes: Wednesday (September 17, 2025): Monohalogenation (Radical Chemistry)

Carbon effect: More e-withdrawing than H

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Notes: Friday (September 19, 2025)

Branched Alkanes have Lower Potential Energy: Why?

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Chapters 3 and 4: Cyclohexane Conformations

Notes: Monday (September 22, 2025)

PowerPoint Slide Pack (NMR)

Worksheet

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Notes: Wednesday (September 24, 2025)

PowerPoint Slide Pack (NMR)

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Chapter 5 (slide pack): Stereochemistry and Stereoisomerism R/S

Notes: Monday (September 29, 2025)

PowerPoint Slide Pack (NMR)

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Notes: Wednesday (October 01, 2025)

Correction to in-class handout

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Notes: Friday (October 03, 2025)

AI and the New Graduate Job Market

Bonus Quiz (Friday, September 08, 2023, NO Notes)

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S_N2 Reactions, Mechanism, and Stereoisomerism

Notes: Monday (October 06, 2025)

Special Note regarding Hyperconjugation and ¹H NMR deshielding

October 06 In-class worksheet (click here)

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Notes: Wednesday (October 08, 2025)

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Notes: Friday (October 10, 2025)

Research Talk (CE)

Supporting Literature

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Notes: Monday (October 13, 2025 see here)

Research Talk (JP)

Supporting Literature

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Alkenes and Their Reactions (slide pack)

Notes: Wednesday (October 15, 2025)

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Notes: Friday (October 17, 2025)

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Notes: Monday (October 20, 2025) Fall Break

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Notes: Wednesday (October 22, 2025)

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Notes: Friday (October 24, 2025)

Chemistry Study Group

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Notes: Monday(October 27, 2025)

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Notes: Wednesday (October 29, 2025)

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Alkynes and Their Reactions

Notes: Monday (November 03, 2025)

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Notes: Wednesday (November 05, 2025)

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Notes: Friday (November 07, 2025) (Heck Rxn Edited 11/13/2025)

Alkene/Alkyne Reaction Summary

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Notes: Monday (November 10, 2025)

Mass Spectrometry (MS)

Infrared Spectroscopy (IR)

(Slide Pack ver 1)

Dissected Slide Packs

Mass Spectrometry (Slide Pack)

13C NMR (Slide Pack)

IR Spectroscopy (Slide Pack)

DOUS (Slide Pack)

Comprehensive Practice Problems

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Notes: Friday (September 15, 2023) PAGE 5 UPDATED

Audio: (September 15, 2023) NO AUDIO TODAY

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Functional Groups (Identifying them) – Prof. Walker won’t cover functional groups explicitly in class – it would be redundant to what’s available, so watching this video is pertinent to learn them!

Friday, Error! Not a valid bookmark self-reference. (see notes from Friday (September 15, 2023)

Video: (September 18, 2023) – the camera system cannot stay focused on one subject, so this session is essentially an audio video to help you supplement the notes that you wrote in class.

Alkane Naming Practice – (CORRECTION): try to work without looking at the answer when naming via the systematic process without using common names or via the method where common names for substituents are allowed.

Mnemonics for ‘Iso’ and ‘Neo’ prefixes of Common Name Alkyl Substituents

(PPT presentation)

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Intro to Newman Projections (click here)

pertinent material starts at 1:50 min

’

from: http://personalpages.manchester.ac.uk/staff/T.Wallace/20412tw2/1.2_anim_ethane.html

Newman Projection for butane (4 min) (click here)

Chapter 3 (slide pack)

Video: (September 20, 2023)

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Quiz 1 (Friday, September 22, 2023, NO Notes)

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Notes: Monday (September 25, 2023)

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Notes: Wednesday (September 27, 2023)

Video: (September 27, 2023)

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Notes: Friday (September 29, 2023)

Video: (September 29, 2023)

Chapter 4 (slide pack)

Notes: Monday (October 02, 2023)

Video: (October 02, 2023) CAMERA FOCUSING ISSUES – AUDIO ONLY

Helpful 5-slide PowerPoint: 1,3-diaxial interactions in cyclohexane rings

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Notes: Wednesday (October 04, 2023)

Video: (October 04, 2023)

Chapter 5 (slide pack)

Notes: Wednesday (October 11, 2023)

Audio: (October 11, 2023) * The last configuration should have been “R” not “S”

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Notes: Friday (October 13, 2023)

Video: (October 13, 2023)

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Notes: Monday (October 16, 2023)

Video: (October 16, 2023)

Chapter 6 (slide pack) Chapter 7 (slide pack)

Notes: Wednesday (October 25, 2023)

Audio/Visual: (October 25, 2023)

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Notes: Friday (October 27, 2023)

Audio/Visual: (October 27, 2023)

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Notes: Monday (October 30, 2023)

Audio/Visual: (October 30, 2023)

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Notes: Wednesday (November 01, 2023): Notes are included in Monday, Oct 30 packet

Audio/Visual: (November 01, 2023)

Chapter 11 (slide pack)

Notes: Monday (November 06, 2023)

Audio/Visual: (November 06, 2023)

Chapter 12 (slide pack)

Notes: Friday (November 10, 2023)

Audio/Visual: (November 10, 2023)

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Notes: Monday (November 13, 2023)

Audio/Visual: (November 13, 2023)

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Notes: Wednesday (November 15, 2023)

Audio/Visual: (November 15, 2023)

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Notes: Monday (November 20, 2023)

Audio/Visual: (November 20, 2023)

Handout (Practice Problems)

Alkene Addition Reaction Overview for Quiz 5

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Notes: Wednesday (November 22, 2023)

Audio/Visual: (November 22, 2023) – No in-person Lecture

Handout (Practice Problems)

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Notes: Monday (November 27, 2023)

Audio/maybe Visual: (November 27, 2023)

Chapter 13 (slide pack) (will be edited)

Notes: Wednesday (November 29, 2023)

Audio/maybe Visual: (November 29, 2023)

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Notes: Friday (December 01, 2023)

Audio/Visual: (December 01, 2023) – No Link

Chapter 10 (slide pack) NMR: Monday December 04

Handout: Wednesday (December 06, 2023)—Flipped class format

Alkene Alkyne Reaction Summaries

General Overview of the Final Exam Content

Tuesday (January 31, 2023)

Ethane Newman Projection Rotational Energy (click here)

Butane Newman Projection Rotational Energy (click here)

pertinent material starts at 2:15 min

Thursday and Tuesday (February 02 and 07)

YouTube Cyclohexane Ring "Flip": (click here)

Helpful 5-slide PowerPoint: 1,3-diaxial interactions in cyclohexane rings

Stereochemistry and determining stereo configuration (useful video here)

Week of February 20, 2023 (Prelude)

Tuesday (February 21)

Thursday (February 23) Part 1 Part 2 Part 3

Tuesday (February 28)

Clutch Prep

Thursday (March 02)

Video Accompaniment (corrected): My written notes only provide an outline of coverage for me to follow during the lecture. If you want a play-by-play script, the notes of one of your classmates from the class on 03/02/2023 will help fill in unviewable text written on the board.

My mnemonics are used to catch a larger audience; if they are unnecessary for you, then optionally disregard them.

Tuesday (March 14)

Video Accompaniment: My written notes only provide an outline of coverage for me to follow during the lecture. If you want a play-by-play script, the notes of one of your classmates from the class on 03/14/2023 will help fill in unviewable text written on the board.

My mnemonics are used to catch a larger audience; if they are unnecessary for you, then optionally disregard them.

Thursday (March 16). YouTube: (Oxymercuration-Demercuration) (Acid-Catalyzed Hydration)

(Compilation of Alkene Addition Reactions)

Video Accompaniment: My written notes only provide an outline of coverage for me to follow during the lecture. If you want a play-by-play script, the notes of one of your classmates from the class on 03/16/2023 will help fill in unviewable text written on the board.

My mnemonics are used to catch a larger audience; if they are unnecessary for you, then optionally disregard them.

Exam 2 Coverage

Tuesday and Thursday (March 21 and March 23) – Unfortunately, I did not press ‘Record to Cloud’ on Zoom, so NO Video Accompaniment this week (Recorder was not started)

Tuesday (March 28), the ozonolysis mechanism was a continuation from the March 23 lecture

Video Accompaniment: My written notes only provide an outline of coverage for me to follow during the lecture. If you want a play-by-play script, the notes of one of your classmates from the class on 03/28/2023 will help fill in unviewable text written on the board.

My mnemonics are used to catch a larger audience; if they are unnecessary for you, then optionally disregard them.

ULA Office Hour: PowerPoint Slides with Problem Solving (Click Here, Monday, March 27, 2023)

Tuesday (April 04)

Video Accompaniment: My written notes only provide an outline of coverage for me to follow during the lecture. If you want a play-by-play script, the notes of one of your classmates from the class on 04/04/2023 will help fill in unviewable text written on the board.

My mnemonics are used to catch a larger audience; if they are unnecessary for you, then optionally disregard them.

Thursday (April 06)

Video Accompaniment: My written notes only provide an outline of coverage for me to follow during the lecture. If you want a play-by-play script, the notes of one of your classmates from the class on 04/06/2023 will help fill in unviewable text written on the board.

My mnemonics are used to catch a larger audience; if they are unnecessary for you, then optionally disregard them.

Tuesday (April 11)

Video Accompaniment: Even though I clicked “Record to Cloud,” the video did not record. This technical glitch is unfortunate, and I am personally sadden.

Complete Chapter 8 Notes for those interested

Thursday (April 13)

Video Accompaniment: My written notes only provide an outline of coverage for me to follow during the lecture. If you want a play-by-play script, the notes of one of your classmates from the class on 04/13/2023 will help fill in unviewable text written on the board.

My mnemonics are used to catch a larger audience; if they are unnecessary for you, then optionally disregard them.

Tuesday (April 18)

Video Accompaniment: My written notes only provide an outline of coverage for me to follow during the lecture. If you want a play-by-play script, the notes of one of your classmates from the class on 04/18/2023 will help fill in unviewable text written on the board.

My mnemonics are used to catch a larger audience; if they are unnecessary for you, then optionally disregard them.

Chapter 9 for Monday, Wednesday, Monday (November 14, 16, 21

Flowchart for S_N1/2 and E1/2 Reaction mechanisms (courtesy of Anshu Yadav – TA)

Thursday (April 20)

Video Accompaniment (Part 1) (Part 2, Easy Fix -- I need to change the microphone settings on my Surface to address the remote headset next time)

My written notes only provide an outline of coverage for me to follow during the lecture. If you want a play-by-play script, the notes of one of your classmates from the class on 04/20/2023 will help fill in unviewable text written on the board.

My mnemonics are used to catch a larger audience; if they are unnecessary for you, then optionally disregard them.

Chapter 12 ppt (April 20)

Exam 3 Coverage (Thanks Aimen)

Chapter 13 ppt ¹H NMR (April 25)

Chapter 13 ppt ¹³C NMR

Chapter 13 (interpreting NMR)

Thursday (February 13)Thursday (February 21)

1,3-diaxial interactions (ppt presentation)

Tuesday (April 25)

Video Accompaniment: My tablet and the MSU IT computer don’t seem to play together nicely. Not only is the video choppy, but the captured video is 8 minutes without me pressing “Stop Recording.”

Rerecorded lecture from kichen (April 26, 2023) “It went more than 20 to 30 min” as hoped. It’s 47 min. Enjoy.

Final Exam Coverage (Thanks for your help Aimen)

Thursday and Tuesday (February 20 and 25)

Thursday (February 27)

Tuesday (March 10) (PowerPoint Presentation)

Thursday (March 12, see March 10 PowerPoint Presentation cont'd)Thursday (April 04)

Tuesday (March 17) Lecture Video (Click here): MP4 format (the recording function started ~15 min late)

There's a part where I say "Two H twos," and I should have said "one H2" or "2 H's". Thanks. There were many distractions on the computer screen (blinking and going from small screen to widescreen) that thankfully did not affect your viewing.Tuesday (April 09)

Exam 2 Thursday March 19 -- online

Tuesday (March 24) Lecture Video (Click here)

NMR Khan Academy: Same discussion as Walker's, but another perspective, different voice

Thursday (March 26)

Lecture Video (Click here)

Tuesday (March 31)

Lecture Video (Click here)

Written Notes: Tuesday (April 21)

Lecture Video

(Part 1)

(Part 2)

(Part 3)

(Part 4)

Thursday (March 14) NMR Chalk Talk;        Chapter 7 (1H NMR) Tables

Tuesday (April 26, T.W.) (Chapter 15 PPT Handout)

Thursday (April 28, G.A.) (plus Chapter 16 PPT Handout)

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