Prof. Xuefei Huang
Professor in Chemistry at Michigan State University
425A Chemistry building
East Lansing MI, 48824
Office: (517) 353-1076
Email: xuefei@chemistry.msu.edu
Biography
I. Education History
B.S. 1994 (Chemistry) University of Science and Technology of China (USTC)
M.A. 1996, M. Phil. 1998 Columbia University in the City of New York
Ph.D. 1999 (Chemistry) Columbia University in the City of New York
II. Professional Experience
1994 - 1999 Graduate Research Assistant, ColumbiaUniversity
1999 - 2001 Postdoctoral Fellow, The Scripps Research Institute
2001 - 2002 Postdoctoral Fellow, Department of Chemistry, ColumbiaUniversity
2002 – 2006 Assistant Professor, Department of Chemistry, University of Toledo
2006 – 2008 Associate Professor, Department of Chemistry, University of Toledo
2008 – 2012 Associate Professor, Department of Chemistry, Michigan State University
2012 –present Professor, Department of Chemistry, Michigan State University
2013 – present Associate Chair for Research, Dept. of Chemistry, Michigan State Univ.
2016 – present Professor, Department of Biomedical Engineering, Michigan State Univ.
2016 – present Member, Institute for Quantitative Health Science and Engineering, Michigan State University
2017 – present MSU Foundation Professor, Michigan State Univ.
III. Honors Received
1990-1991 People’s Fellowship, USTC
1992 Zhang Zhongzhi Award for Outstanding Undergraduates, USTC
1993 Yi Lida Award for Outstanding Laboratory Works, USTC
1994 – 1999 Faculty Fellowship, Columbia University
1999 Pegram Award for Excellent Graduate Studies, Columbia University
2006 – 2011 NSF CAREER award
2007 Dion D. Raftopoulos Outstanding Research Award, Sigma Xi, Univ. of Toledo
2008 Distinguished Faculty Award, Chinese-American Chemistry Prof. Association
2009 New Investigator Award, American Chemical Society Carbohydrate Division
2011 Horace S. Isbell Award, American Chemical Society Carbohydrate Division
2013 ACS Fellow
2017 Melville L. Wolfrom Award, American Chemical Society Carbohydrate Division
2020 Fellow, the American Association for Advancement of Science
2020 William J. Beal Outstanding Faculty Award, Michigan State University
IV. Professional Affiliations
American Chemical Society
American Chinese Chemistry Professor Association
American Association for Advancement of Science
American Association for Cancer Research
V. Courses Taught
General Chemistry Laboratory
Organic Chemistry I & II
Advanced Organic Chemistry
Spectroscopic Methods & Analysis
Organic Synthesis
Intermediate Organic Chemistry
Physical Organic Chemistry
Special Topics in Chemical Biology
Chemistry and Biology of Pathogens
Molecular (Neuro) Imaging
VI.Fundings
CURRENT SUPPORT
National Institute of General Medical Sciences, NIH
Title: “Enabling Synthesis and Biological Studies of Homogeneous Heparan Sulfate and Chondroitin Sulfate Glyco-polypeptides and Proteoglycans”
PI: Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill) 1/1/2021 – 12/31/2024. Award amount: $1,221,309 (R01 GM72667)
National Institute of General Medical Sciences, NIH
Title: “Enabling Synthesis and Biological Studies of Homogeneous Heparan Sulfate and Chondroitin Sulfate Glyco-polypeptides and Proteoglycans - supplement”
PI: Xuefei Huang, co-PI: Jian Liu (UNC, Chapel Hill) 1/1/2021 – 12/31/2021. Award amount: $212,182 (R01 GM72667-14S1) Supplement to acquire a mass spectrometry instrument.
National Cancer Institute, NIH
Title: “Engineering Bacteriophage Qβ Conjugates with Tumor Associated Carbohydrate Antigens as Multi-component Anti-cancer Vaccines”
PI: Xuefei Huang, co-PIs: Vilma Yuzbasiyan-Gurkan (MSU), Paulo Vilar Saavedra (MSU) 1/1/2018 – 12/31/2022. Award amount: $2,400,000 (R01 CA225105)
https://www.eurekalert.org/pub_releases/2018-03/msu-vpc030218.php
https://futurism.com/animal-cancer-vaccine-awarded-grant/
http://wearethecure.org/virus-like-particle-could-lead-to-new-canine-cancer-vaccine/
https://msutoday.msu.edu/news/2018/virus-like-particle-could-lead-to-new-cancer-vaccine/
https://aggregator.leafscience.org/virus-like-particle-could-lead-to-new-cancer-vaccine/
National Cancer Institute, NIH
Title: “Generation of Active Immunity against Cytotoxic Oligomeric Tau Species”
PI: Xuefei Huang, co-PI: Rakez Kayed (Univ. of Texas, Medical Branch) 7/1/2019 – 12/31/2022. Award amount: $375,606 (R01 CA225105-02S1)
Michigan State University Foundation, MSU
Title: “Preclinical Development of MUC1 Based Anti-cancer Immunotherapy”
PI: Xuefei Huang (MSU); co-PIs: Vilma Yuzbasiyan-Gurkan, Paulo Vilar Saavedra, Tim Whitehead, Anas Al-janadi, Xiangshu Jin, Deimante Tamkus 7/1/2018 – 6/30/2022. Award amount: $400,000
National Institute of Allergy and Infectious Diseases, NIH
Title: “Synthetic Glycan Conjugates with Bacteriophage Qbeta for Broad Spectrum Antisalmonella Vaccines”
PI: Xuefei Huang, co-PI: Sharon Tennant (University of Maryland) 07/16/2019 – 06/30/2024. Award amount: $1,500,000 (R01AI146210)
National Institute of General Medical Sciences, NIH
Title: “Diverse Heparan Sulfate Oligosaccharide Libraries for Understanding and Therapeutically Manipulating Glycosaminoglycans”
PI: Vijayakanth Pagadala (Glycan Therapeutics), Subcontractor: Xuefei Huang, Linda Hsieh-Wilson (Caltech) 8/1/2019 – 1/31/2022. Award amount: ~ $2,500,000 (R44 GM134738)
COMPLETED SUPPORTS
VII. Service
A) Activities at the University of Toledo
Graduate recruiting committee, member 2002 - 2008
Colloquium committee, chair 2003 - 2004
Faculty search committee for chemistry department 2002 – 2005
Faculty search committee for medicinal chemistry dept. 2006
Departmental library liaison 2004 – 2008
Chair advisory committee 2004 – 2005, 2006 - 2008
Departmental personnel committee 2007 - 2008
Departmental merit committee 2007 - 2008
College of Arts & Sciences council, member 2004 – 2007
B) Activities at Michigan State University
Chair advisory committee 2008 – 2010
Graduate student examination committee 2008 – present
Awards committee 2009 – 2011
Departmental colloquium committee chair 2011
Graduate admission committee 2010 – present
Departmental colloquium committee chair 2012 - 2013
Associate chair for research 2013 – present
Reappointment, Tenure & promotion committee, chair 2013 – 2014
Chemistry awards committee, chair 2013 - present
BME awards committee, chair 2018 – present
IQ Leadership Committee 2018 - present
Chinese Faculty Club, chair 2019 – 2020
C) Other Professional Activities
Oct. 2007 Ad hoc member, NIH study sections HT
June 2008 Ad hoc member, NIH study section SBCA
Oct. 2008 NSF CAREER proposal review panelist
June 2009 Member, NIH study section ZRG1 BCMB-B
July 2009 Member, NIH study section ZRG1 BCMB-A
July 2009 Member, NIH study section “Expanding the Chemical Space for Carbohydrates"
Oct. 2009 Member, NIH study section ZRG1 BCMB
March. 2010 Member, NIH study section ZRG1 BCMB-B
May 2010 Member, NIH study section ZRG1 CB-B
Oct. 2011 Member, Mail Reviewer, NIH K99 review panel
Mar. 2012 Member, Mail Reviewer, NIH special emphasis panel ZCA1 SRLB-9
Feb 2013 Member, Member, NIH study section MSFE
Jan. 2014 Member, NIH study section ZAI1 SV-A (J3)
2014 – 2018 Member, NIH study section SBCA
Feb. 2019 Member, NIH special emphasis panel, U01 Technologies for Analysis of Glycans
March 2020 Member, NIH special emphasis panel, New Innovator DP2 Award
July 2020 Member, NIH special emphasis panel, MOSAIC K99/R00 Award
March 2021 Member, NIH special emphasis panel, New Innovator DP2 Award
2005
Organizer of the 1st Annual Midwest Carbohydrate and Glycobiology Symposium, Toledo, OH
2006
Section chair, 2nd Annual Midwest Carbohydrate and Glycobiology Symposium, Detroit, MI
2007
Discussion leader, Gordon Research Conference on Carbohydrates
2007
Section chair, 3rd Annual Midwest Carbohydrate and Glycobiology Symposium, Columbus, OH
2008 – present
Board member of the Chinese-American Chemistry Professor Association
2009
Section chair, 5th Annual Midwest Carbohydrate and Glycobiology Symposium, Cincinnati, OH
2010 - 2011
Secretary of the American Chemical Society Carbohydrate Division
2010
Organizer and Chair of "Petite and Sweet: Glyco-nanotechnology as a Bridge to New Medicines" symposium, ACS 240th National Meeting, Boston, MA
2010
Chair-elect, American Chemical Society MSU local section
2010
Section chair, 6th Annual Midwest Carbohydrate and Glycobiology Symposium, Toledo, OH
2011
Chair, American Chemical Society MSU local section
2011
Organizer of the 7st Annual Midwest Carbohydrate and Glycobiology Symposium, East Lansing, MI
2011
One of the two editors for ACS Symposium book, "Glyco-nanotechnology as a Bridge to New Medicines" (Dr. Joseph Barchi from NCI is the other editor)
2011 - present
Member, Editorial Advisory Board, Carbohydrate Research
2012 - 2013
Program Chair of the American Chemical Society Carbohydrate Division
2012 - present
Associate Editor, Journal of Carbohydrate Chemistry
2014
Chair-elect, the American Chemical Society Carbohydrate Division
2015
Chair, the American Chemical Society Carbohydrate Division
2016
Past chair, the American Chemical Society Carbohydrate Division
2018
Organizer of the 14th Annual Midwest Carbohydrate and Glycobiology Symposium, East Lansing, MI
2019
Organizer of the Chemistry and Biology of Pathogens Symposium, East Lansing, MI
Review proposals for:National Science Foundation
National Institutes of Health
Petroleum Research Foundation of the American Chemical Society
Bicentennial Program in Science and Technology of Chile
Natural Sciences and Engineering Research Council of Canada (NSERC)
Chilean National Commission for Science and Technology Research
North Carolina Biotechnology Center
Ohio Cancer Associate
Central Michigan University
Austrian Programme for Advanced Research and Technology
Danish Council for Independent Research
Israel Science Foundation
Research Cooperation
CUNY
Netherlands Organization for Scientific Research
Czech Science Foundation
New Zealand Genesis Oncology Trust
Review manuscripts for:
(~550 manuscripts) for J. Am. Chem. Soc., J. Org. Chem., Chem. Commun., Org. Lett., Angew. Chemie., Tetrahedron, Tetrahedron Lett., Eur. J. Org. Chem., Synthesis, Adv. Synth. Catal., Cancer Immun. Immunother., Carbohydr. Res., Chirality, Bioorg. Med. Chem., Lett. Org. Chem., Curr. Med. Chem., J. Carbohydr. Chem., Org. Biomol. Chem., Biochemistry, Mol. Biosys., Med. Chem. Rev., J. Med. Chem., Molecular Diversity, Science China Chemistry, Anal. Chem., Analyst, Glycobiology, Proc. Nat. Acad. Sci. USA, Nanoscale, Appl. Microbiol. Biotech., Adv. Func. Mater., Int. J. Mol. Sci. Beilstein J. Org. Chem.; ACS Chem. Biol. Etc.
Review various faculties for tenure and/or promotion
D) Service to the Community
Give chemistry demos during National Chemistry Day 2003 - 2008
Judge, Northwest District Science Day 2005
Speaker and organizer, Saturday Morning Sciences, a community outreach seminar program 2005 - 2008
Frontiers in Science program for secondary science teachers 2011
VIII. Publications
Please click here for the complete list of journal articles
IX. Invited seminars
2004
Department of Medicinal and Biological Chemistry, The University of Toledo
Department of Chemistry, KenyonCollege
Department of Chemistry, WrightStateUniversity
2005
Department of Chemistry, YoungstownStateUniversity
Department of Chemical and Environmental Engineering, The University of Toledo
Department of Chemistry, University of Georgia
Department of Chemistry, Georgia State University
Department of Chemistry, Wayne State University
Department of Chemistry, University of Guelph
2006
Department of Chemistry, University of Akron
Department of Chemistry, University of California, Davis
Department of Chemistry, Cleveland State University
Department of Chemistry, Duke University
Department of Chemistry, University of South Carolina
Department of Chemistry, North Carolina State University
Department of Chemistry, West Virginia University
Department of Chemistry, Pennsylvania State University
Department of Chemistry, Michigan State University
Department of Chemistry, Columbia University
Department of Chemistry, Hunter College, City University of New York
2007
Department of Bioengineering, University of Toledo
Department of Chemistry, John Carroll University
Department of Medicinal and Biological Chemistry, University of Toledo
Department of Chemistry, Tulane University
National Institutes of Health, NIH Workshop on Carbohydrates
Faculty of Agriculture and Life Science, Hirosaki University, Japan
National Research Laboratory of Natural and Biomimetic Drug, Peking University, China
2008
Department of Chemistry, Oakland University
National Institutes of Health, NIH Glycoscience day
School of Chemistry and Materials Science, USTC, Hefei, China
Department of Chemistry, University of New Mexico
Department of Chemistry, University of Missouri, St. Louis
2009
Department of Chemistry and Chemical Biology, Cornell University
Department of Chemistry, Binghamton University
Laboratory of Medicinal Chemistry, National Cancer Institute
National Institutes of Health, NIH Workshop on Carbohydrate Microarray Development
2010
Department of Chemistry, University of New Orleans
Department of Chemistry, Osaka University, Japan
Department of Biomedical Engineering, University of Michigan
Department of Medicinal Chemistry, University of North Carolina, Chapel Hill
2011
Department of Chemistry, Purdue University
Shanghai Institute of Organic Chemistry, China
Department of Chemistry, Shandong University, China
Department of Chemical Biology, Xiamen University, China
Department of Chemistry, Shanghai Jiaotong University, China
2012
Department of Chemistry, Central Michigan University
Department of Melanoma Medical Oncology Research, M. D. Anderson Cancer Center
Department of Chemistry, Brown University
2013
Department of Chemistry, University of Pittsburgh
2015
Department of Chemistry, The Scripps Research Institute
Department of Chemistry, University of Michigan,Dearborn
College of Pharmacy, University of Wisconsin
Department of Chemistry, Binghamton University
Department of Chemistry, Wayne State University
2016
Department of Chemistry and Biochemistry, University of Notre Dame
Department of Chemistry, University of Colorado
Department of Chemistry, Rensselaer Polytechnic Institute
Department of Chemistry, Georgia State University
Department of Chemistry and Biochemistry, University of Arkansas
2017
Department of Chemistry, Northeastern University
Department of Chemistry, Old Dominion University
National Center for Carbohydrate Synthesis and Engineering, Jiangxi Normal University
Department of Chemistry, York University, Canada
Department of Chemistry, University of Toronto, Canada
2019
Department of Chemistry & Biochemistry, University of Maryland, College Park
College of Pharmacy, Sichuan University, Chengdu, China
2020
Department of Chemistry, University of Alberta, Edmonton, Canada
National Glycoengineering Center, Shandong University, Shandong, China
2021
China Ocean University, Qingdao, Shandong, China