The Bruening Group
Department of Chemistry
Michigan State University
 Ultrathin Films for Separations, Analysis and Catalysis


Rapid Protein Digestion in Trypsin-Containing Membranes

Brush-Modified Membranes for Protein Purification

Multilayered Polyelectrolyte Membranes

Catalytic Membranes for Pollutant Oxidation

On-probe Capture of Phospho-peptides for Mass Spectrometry

Selective Catalysis with Nanoparticles

SEM Images

Alumni

Publications

Graduate School at MSU

MSU chemistry

DOE Support

NIH Support

NSF PIRE Support

Who are we?  We're a  research group in the chemistry department at Michigan State University led by Dr. Merlin Bruening.  The group currently consists (winter 2010) of twelve graduate students, two undergraduate students,and one postdoctoral associate. 

What do we do?  We develop new thin films for protein purification in porous supports, gas separations, membrane-based water reclamation, purification for MALDI mass spectrometry, and selective catalysis. In some cases, students spend a month or two in France or Ukraine in collaborative research. Our graduates move on to a wide range of industrial positions.     

What tools do we use?  We use surface infrared spectroscopy, field-emission scanning electron microscopy, electrochemistry, mass spectrometry, ellipsometry, nanofiltration, and atomic force microscopy.  Whenever possible we try to exploit characterization techniques that don't require ultrahigh vacuum so we can simulate actual conditions. 

More Information?  Click on any of the links above for other graphics and descriptions.  If you are interested in graduate work in chemistry at Michigan State University, click here.  We also have a list of publications describing prior work.  If you have specific questions, send e-mail to bruening@chemistry.msu.edu
 

group picture The Bruening group  (2009):  From left to right, front:  Chao Cheng, Lu Ouyang, Fei Xu, Nishotha Anuraj, David Dotzauer, Yujing Tan, Xiaojie Dong, and Elizabeth Igrisan.
back:  Guanqing Liu, Mukesh Vyas, Seth Hogg, Maneesha Adusumilli, Merlin Bruening, Weihan Wang, and Sebastian Grajales. 

Overview of membrane work

Our group modifies membranes with thin films for applications such as water softening, protein and peptide purification, and catalysis, including protein digestion.