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Department of Chemistry Michigan State University |
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Brush-Modified Membranes for Protein Purification Multilayered Polyelectrolyte Membranes Membrane-Based Antibody Arrays On-probe Capture of Phospho-peptides for Mass Spectrometry |
Who
are
we? We're a research group in the chemistry
department at Michigan State
University
led by Dr.
Merlin Bruening. The group currently consists (winter 2009)
of fourteen graduate
students, two undergraduate students,and one postdoctoral associate who
will join us in February.
What do we do? We develop new thin films for protein purification in porous supports, gas separations, membrane-based water reclamation, purification for MALDI mass spectrometry, and selective catalysis. In some cases, students spend a month or two in France or Ukraine in collaborative research. What tools do we use? We use surface infrared spectroscopy, field-emission scanning electron microscopy, electrochemistry, mass spectrometry, ellipsometry, nanofiltration, and atomic force microscopy. Whenever possible we try to exploit characterization techniques that don't require ultrahigh vacuum so we can simulate actual conditions. More Information? Click on
any of
the links above for other graphics and descriptions. If you are
interested
in graduate work in chemistry at Michigan State University, click
here. We also have a list of
publications describing prior work. If you have specific
questions, send e-mail to bruening@chemistry.msu.edu
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The Bruening group (spring
2008): From left to right, front:
Parul Jain, Xiaojie Dong, Fei Xu, Lu Ouyang, and Somnath Bhattacharjee.
Not pictured: Elizabeth Igrisan, Yujing Tan.back: Maneesha Adusumilli, Guanqing Liu, Weihan Wang, Jorge Macanás, Sebastian Grajales, David Dotzauer, and Merlin Bruening.
Schematic diagram of analytes approaching a multilayer
polyelectrolyte membrane. Multilayer membranes can separate
monovalent and divalent anions (Cl-/SO42-
selectivities as high as 1000) as well as small organic molecules such
as glucose and sucrose. In some cases, we have also separated
gases such as O2 and N2. Because the
membranes are ultrathin, they allow high fluxes. |